Speaker: Prof. Peter J. Sadler, University of Warwick, Chemistry Department
16:00-17:30 p.m., November 23, 2023, GMT+8
C101, College of Chemistry and Molecular Engineering, PKU
I will discuss the role of metallomics in the design of catalytic metal complexes as novel drugs with new mechanisms of action. The mechanisms will include redox catalysis and transfer hydrogenation, molecular motors, and photocatalysis. Challenges include the controlled activation of produgs, and the demonstration of in-cell catalysis. Our studies illustrate the crucial roles of the metal, its oxidation state, the coordinated ligands, and the coordination geometry.
College of Chemistry and Molecular Engineering, PKU