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[Lecture] The Hippo Signaling Pathway-Function, Regulation, and Evolution
Jul. 24, 2024

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Speaker: Duojia Pan, PhD, Bashour Distinguished Professor and Chair, Department of Physiology, UT Southwestern Medical Center, Investigator, Howard Hughes Medical Institute Member, US National Academy of Science

Time: 10:00-11:30 a.m., July 24, 2024, GMT+8

Venue: Rm. 101, Jin-Guang Life Science Building, PKU


Dr. Pan has a long-standing interest in molecular mechanisms underlying growth control and tissue homeostasis. He earned a PhD at UCLA through the renowned CUSBEA program and then had postdoctoral training with Prof. Gerald Rubin at UC Berkeley. Dr. Pan's research has recently focused on the Hippo pathway, which controls organ size in all animals. Using Drosophila and mice as genetic models, his works have systematically decoded key molecular components of the Hippo pathway, including its core kinase cascade, the downstream transcriptional machinery, and upstream regulators. Dr. Pan has further established a conserved role for Hippo signaling in mammalian tissue growth, regeneration, and tumorigenesis. For those landmark discoveries, he has been recognized as an investigator of the Howard Hughes Medical Institute and a member of the U.S. National Academy of Sciences.

Source: School of Life Sciences, PKU